I-99% i-Tianeptine sodium usawoti CAS 30123-17-2
Ukucaciswa
| INTO | IZINGA | RESULT |
| Ukubukeka | Impushana emhlophe ukuya kokuphuzi | I-crystalline powder emhlophe |
| Ukuncibilika | Incibilika ngokukhululekile Emanzini kanye i-methanol ne-dichloromethane | Kuyavumelana |
| Ukuhlonza | Nge-IR, Ukufanisa nezinga lokusebenza | Kuyavumelana |
| (2) Inikeza ukusabela kwe-sodium | Kuyavumelana | |
| Ukungcola A | ≤0.1% | Ayitholakali |
| Izinhlanganisela ezihlobene | Noma yikuphi ukungcola okukodwa okuphezulu≤0.1% | 0.060% |
| Ukungcola okuphelele≤0.4% | 0.36% | |
| I-Residual Solvents (GC) | I-Acetidin≤ 0.5% | ND |
| I-Dichloromethane≤ 0.06% | ND | |
| I-Methanol≤ 0.3% | ND | |
| I-acetone≤ 0.5% | 0.29% | |
| I-acetonitrile≤0.041% | 0.022% | |
| I-Ethanol≤0.5% | ND | |
| N, N-dimethylformamide≤0.088% | ND | |
| Amanzi | ≤ 5.0% | 3.8% |
| I-Assay (HPLC) | 99.0% -101.0% (Kusisekelo se-anhydrous) | 99.70% |
Isicelo
I-Tianeptine sodiumusawotii-tricyclic antidepressant.Indlela yayo ye-antidepressant yehlukile kuleyo yama-tricyclic antidepressants endabuko.Ingakhuphula ukuphinda kuthathwe kwe-5-HT ku-synaptic cleft.Imiphumela ye-HT neuronal conduction.Akukho ukuhambisana kwe-choline noma i-adrenergic receptors.Ukusebenza kwe-antidepressant kufana nalokhu kwe-tricyclics, kodwa ukubekezelelana kungcono kunaleyo ye-tricyclics.Ukuze ekwelapheni ukucindezeleka okuncane, okumaphakathi noma okunzima, ukucindezeleka kwe-neurogenic kanye ne-reactive, ukukhathazeka nokucindezeleka ngokomzimba, ikakhulukazi ukungakhululeki kwamathumbu, nokukhathazeka nokucindezeleka ezigulini ezithembele otshwaleni ngesikhathi sokuhoxiswa.
